Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.71 |
| ▸ | MPO | P05164 | 3/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SPR | P35270 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036033 | 0.91 | MPO (0.75) | MTNR1AMPOTRPV1SPRNOTUM | |
| SCHEMBL30952642 | 0.87 | MTNR1A (0.72) | MTNR1ATRPV1MEN1KMT2AMTNR1B | |
| SCHEMBL1131155 | 0.86 | TRPV1 (0.78) | MTNR1AMPOTRPV1SPRNOTUM | |
| SCHEMBL30275087 | 0.86 | HTR2A (0.63) | MTNR1AMPOMEN1KMT2ASPR | |
| SCHEMBL31381360 | 0.83 | SPR (0.54) | MTNR1AMPOMEN1KMT2ASPR | |
| SCHEMBL1068274 | 0.83 | MTNR1A (1.00) | MTNR1ATRPV1MEN1KMT2A | |
| SCHEMBL4488812 | 0.83 | MTNR1A (0.81) | MTNR1AMPOMEN1KMT2ASPR | |
| SCHEMBL31381358 | 0.81 | SPR (0.54) | MTNR1AMPOTRPV1MEN1KMT2A | |
| SCHEMBL28872473 | 0.81 | SPR (0.62) | MTNR1AMEN1KMT2ASPRNOTUM | |
| SCHEMBL1129785 | 0.80 | MTNR1A (0.77) | MTNR1ATRPV1MEN1KMT2AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140687-A1 | S1PR2 REGULATOR AND USE THEREOF | 北京昌平实验室 | 2024-07-04 | — | — | WO | disclosed |
| CN-118255830-A | S1PR2 modulators and uses thereof | 北京昌平实验室 | 2024-06-28 | — | — | CN | disclosed |