Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29181034 | 0.88 | GPR119 (0.46) | GPR119NR1H2LIPEHDAC1HDAC2 | |
| SCHEMBL30837378 | 0.88 | GPR119 (0.46) | GPR119NR1H2LIPEHDAC1HDAC2 | |
| SCHEMBL31107652 | 0.85 | MAPT (0.53) | GPR119NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL25932930 | 0.84 | NR1H2 (0.44) | GPR119NR1H2NR1H3LIPEHDAC1 | |
| SCHEMBL25932939 | 0.83 | NR1H2 (0.43) | GPR119NR1H2NR1H3LIPEHDAC1 | |
| SCHEMBL29181037 | 0.79 | LMNA (0.47) | GPR119NR1H2EEDRBBP4SUZ12 | |
| SCHEMBL27399965 | 0.79 | GPR119 (0.67) | GPR119NR1H2LIPEMEN1KMT2A | |
| SCHEMBL20511076 | 0.79 | GPR119 (0.67) | GPR119NR1H2LIPEMEN1KMT2A | |
| SCHEMBL30952676 | 0.79 | USP30 (0.39) | GPR119HDAC1HDAC2USP30 | |
| SCHEMBL25155694 | 0.78 | USP30 (0.43) | GPR119NR1H2EEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121709-A1 | PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS | PFIZER INC. (US) | 2024-06-13 | — | — | WO | disclosed |