Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952660 | 0.88 | LMNA (0.44) | GPR119LMNACYP2C19 | |
| SCHEMBL30083233 | 0.85 | SMN1; SMN2 (0.44) | ACACB | |
| SCHEMBL30083142 | 0.80 | BACE1 (0.45) | GPR119LMNACYP2C19 | |
| SCHEMBL31218062 | 0.79 | ACACB (0.39) | ACACB | |
| SCHEMBL24732366 | 0.79 | ACACB (0.39) | ACACB | |
| SCHEMBL30952684 | 0.79 | GPR119 (0.45) | USP30GPR119HDAC1HDAC2 | |
| SCHEMBL30837378 | 0.78 | GPR119 (0.46) | GPR119LMNAHDAC1HDAC2 | |
| SCHEMBL29181034 | 0.78 | GPR119 (0.46) | GPR119LMNAHDAC1HDAC2 | |
| SCHEMBL30952659 | 0.77 | RET (0.45) | GPR119 | |
| SCHEMBL30952662 | 0.77 | RET (0.45) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121709-A1 | PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS | PFIZER INC. (US) | 2024-06-13 | — | — | WO | disclosed |