Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL309539

Cc1c(Cl)ccc(Cl)c1C.N.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
CES1 P23141 1/20 0.39
CYP2A6 P11509 2/20 0.37
CYP1A2 P05177 1/20 0.37
MAPT P10636 2/20 0.37
TSHR P16473 3/20 0.35
LMNA P02545 3/20 0.35
CYP3A4 P08684 4/20 0.35
PIK3CA P42336 1/20 0.35
AHR P35869 1/20 0.35
TP53 P04637 1/20 0.35
RAPGEF4 Q8WZA2 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPK1 P28482 1/20 0.32
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
CSNK2A1 P68400 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6681654 0.96 ALDH1A1 (0.48) ALDH1A1CES1CYP2A6CYP1A2MAPT
Ammonia Solution, Strong SCHEMBL3875612 0.87 CYP3A4 (0.39) ALDH1A1CES1CYP2A6CYP1A2MAPT
SCHEMBL5734545 0.83 CYP3A4 (0.40) ALDH1A1CES1CYP2A6CYP1A2MAPT
SCHEMBL900037 0.79 ALDH1A1 (0.42) ALDH1A1CES1CYP2A6CYP1A2MAPT
Ammonia Solution, Strong SCHEMBL1640555 0.79 ALDH1A1 (0.62) ALDH1A1CYP2A6CYP1A2MAPTTSHR
SCHEMBL918736 0.78 CES1 (0.38) ALDH1A1CES1MAPT
SCHEMBL15430786 0.78 ALDH1A1 (0.37) ALDH1A1CES1MAPTCSNK2A1
SCHEMBL3971917 0.78 ALDH1A1 (0.61) ALDH1A1CES1TSHRCYP3A4PIK3CA
SCHEMBL17065148 0.78 CES1 (0.38) ALDH1A1CES1MAPTCSNK2A2CSNK2B
SCHEMBL335595 0.78 CYP3A4 (0.48) ALDH1A1MAPTTSHRLMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2059267-B1 TEMPORAL PHOTO-BLEACHING OF COLORED LENS CARE SOLUTIONS NOVARTIS AG (CH) 2012-04-18 EP disclosed
US-8091568-B2 Temporal photo-bleaching of colored lens care solutions and use thereof NOVARTIS AG (CH) 2012-01-10 US disclosed
US-8062607-B2 Lens care methods and kits NOVARTIS AG (CH) 2011-11-22 US disclosed
EP-2049163-B1 LENS CARE METHODS AND KITS NOVARTIS AG (CH) 2010-04-28 EP disclosed
US-20090324466-A1 Lens care methods and kits ALCON INC. (CH) 2009-12-31 US disclosed
US-20090199878-A1 TEMPORAL PHOTO-BLEACHING OF COLORED LENS CARE SOLUTIONS AND USE THEREOF ALCON INC. (CH) 2009-08-13 US disclosed
EP-2059267-A1 TEMPORAL PHOTO-BLEACHING OF COLORED LENS CARE SOLUTIONS AND USE THEREOF Novartis AG (CH) 2009-05-20 EP disclosed
EP-2049163-A1 LENS CARE METHODS AND KITS Novartis AG (CH) 2009-04-22 EP disclosed
WO-2008021349-A1 TEMPORAL PHOTO-BLEACHING OF COLORED LENS CARE SOLUTIONS AND USE THEREOF NOVARTIS AG (CH) 2008-02-21 WO disclosed
WO-2008008525-A1 LENS CARE METHODS AND KITS NOVARTIS AG (CH) 2008-01-17 WO disclosed
EP-0097042-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1988-02-03 EP disclosed
US-4451558-A PHENOL CYAN COUPLER WITH 2-(ALKYLSULFONYL-PHENYL-UREIDO) GROUP, DISPERSED IN PHTHALIC ESTER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-05-29 US disclosed
EP-0097042-A2 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1983-12-28 EP disclosed
EP-0073145-A1 A phenol cyan coupler for silver halide color photographic material KONICA CORPORATION (JP) 1983-03-02 EP disclosed