SCHEMBL30954048

SCHEMBL30954048

COc1c(Cl)cc2c(c1C(=O)O)OCCN2Cc1ccsc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NAAA Q02083 1/20 0.33
DRD3 P35462 4/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90B1 P14625 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
DRD2 P14416 2/20 0.32
HTR1A P08908 1/20 0.32
DRD4 P21917 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
CCR2 P41597 1/20 0.32
NSD2 O96028 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27435420 1.00 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL27435408 0.91 HSP90AA1 (0.40) ALDH1A1MEN1KMT2AKDM4ENAAA
SCHEMBL27435528 0.88 KCNA3 (0.41) ALDH1A1KDM4EHSD17B10DRD3DRD2
SCHEMBL27435254 0.86 TP53 (0.42) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL30954067 0.86 TP53 (0.42) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL30954045 0.83 POLB (0.42) ALDH1A1KDM4EHSD17B10DRD3SMN1; SMN2
SCHEMBL27433854 0.83 POLB (0.42) ALDH1A1KDM4EHSD17B10DRD3SMN1; SMN2
SCHEMBL30954160 0.81 KDM4E (0.40) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL27435335 0.81 KDM4E (0.40) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL27435508 0.80 DRD3 (0.41) ALDH1A1MEN1KMT2ADRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP claimed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO claimed
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed