Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503279 | 0.83 | L3MBTL1 (0.36) | PTGS1PTGS2DAOCYP11B1CYP11B2 | |
| SCHEMBL30954803 | 0.76 | MAPT (0.45) | POLB | |
| SCHEMBL30954800 | 0.76 | DAO (0.39) | DAO | |
| SCHEMBL29829548 | 0.72 | BRS3 (0.38) | PTGS1PTGS2HTR2AKCNH2 | |
| SCHEMBL15746728 | 0.72 | BRS3 (0.38) | PTGS1PTGS2HTR2AKCNH2 | |
| SCHEMBL1503241 | 0.69 | HDAC1 (0.39) | PTGS1PTGS2 | |
| SCHEMBL15437070 | 0.69 | TAAR1 (0.54) | PTGS1PTGS2DAOTAAR1TRPA1 | |
| SCHEMBL7470790 | 0.67 | MPO (0.65) | PTGS1PTGS2DAOTAAR1MPO | |
| SCHEMBL8431907 | 0.67 | PTGS1 (0.52) | PTGS1PTGS2DAOTAAR1SLC5A1 | |
| SCHEMBL7437052 | 0.66 | TAAR1 (0.68) | PTGS1PTGS2DAOTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687538-B1 | METHODS OF TREATING ELEVATED PLASMA CHOLESTEROL | MONTREAL HEART INST (CA) | 2024-04-17 | — | — | EP | claimed |