Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954801 | 0.76 | PTGS1 (0.39) | POLB | |
| SCHEMBL30954800 | 0.73 | DAO (0.39) | MAPTALDH1A1MAOBRAB9ANPC1 | |
| SCHEMBL1503105 | 0.73 | P4HTM (0.46) | MAPTALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL1503231 | 0.71 | ALDH1A1 (0.42) | MAPTALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL12444364 | 0.71 | ALOX5 (0.40) | MAPTALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL1503279 | 0.70 | L3MBTL1 (0.36) | L3MBTL1KDM4E | |
| SCHEMBL27616587 | 0.69 | MAPT (0.69) | MAPTALDH1A1KMT2AL3MBTL1LMNA | |
| Acetic Acid SCHEMBL27812972 | 0.68 | MAOB (0.43) | MAPTALDH1A1KMT2ALMNAKDM4E | |
| Acetic Acid SCHEMBL27833084 | 0.66 | GRIN1 (0.40) | MAPTALDH1A1KDM4ETHRBGAA | |
| SCHEMBL7157507 | 0.65 | EGFR (0.56) | MAPTALDH1A1KMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687538-B1 | METHODS OF TREATING ELEVATED PLASMA CHOLESTEROL | MONTREAL HEART INST (CA) | 2024-04-17 | — | — | EP | claimed |