Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954801 | 0.83 | PTGS1 (0.39) | P2RX7SLC5A1SLC5A2CYP11B1CYP11B2 | |
| SCHEMBL30954800 | 0.78 | DAO (0.39) | DAO | |
| SCHEMBL4306646 | 0.76 | HCAR2 (0.35) | HCAR2 | |
| SCHEMBL1503195 | 0.74 | HCAR2 (0.36) | HCAR2ADRB2ADRB1 | |
| SCHEMBL15746682 | 0.71 | KDM4E (0.48) | L3MBTL1KDM4EPTGS1PTGS2 | |
| SCHEMBL30954803 | 0.70 | MAPT (0.45) | L3MBTL1KDM4E | |
| SCHEMBL28367193 | 0.67 | TAAR1 (0.54) | ELOVL1PTGS1PTGS2 | |
| SCHEMBL321367 | 0.66 | TAAR1 (0.45) | PTGS1PTGS2 | |
| SCHEMBL28791544 | 0.65 | L3MBTL1 (0.42) | L3MBTL1HCAR2PTGS1PTGS2 | |
| SCHEMBL1503228 | 0.64 | MAOB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300433-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | Ambrilia Biopharma Inc. (CA) | 2011-03-30 | — | — | EP | claimed |