SCHEMBL30954987

SCHEMBL30954987

C=C(C)c1ncc(F)cc1-c1c(F)cccc1F

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SRC P12931 5/20 0.33
BTK Q06187 4/20 0.33
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
LYN P07948 2/20 0.32
PDGFRB P09619 1/20 0.31
FGFR1 P11362 1/20 0.31
PDGFRA P16234 1/20 0.31
WEE1 P30291 1/20 0.30
GPBAR1 Q8TDU6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29599902 0.79 TTR (0.41) SRCBTKLYN
SCHEMBL29601005 0.78 PDK2 (0.38) SRCBTKPDGFRBFGFR1PDGFRA
SCHEMBL30955012 0.71 ALOX5AP (0.36) SRCBTKALOX5APFEN1LYN
SCHEMBL18865713 0.69 APP (0.32)
SCHEMBL30954919 0.69 GABRA1 (0.32)
SCHEMBL2654021 0.65 GABRG2 (0.42) ALOX5APFEN1
SCHEMBL27936909 0.65 CTSA (0.37)
SCHEMBL26186907 0.64 MAPK14 (0.38)
SCHEMBL38655387 0.62
SCHEMBL1395991 0.61 AGBL2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626546-A1 HETEROCYCLIC COMPOUND AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2025-10-08 EP disclosed
WO-2024116086-A1 HETEROCYCLIC COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-06-06 WO disclosed