Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29599902 | 0.82 | TTR (0.41) | SRCBTKKDM4E | |
| SCHEMBL29600750 | 0.81 | BDKRB1 (0.35) | PDK2ALPLABL1BDKRB1 | |
| SCHEMBL16634586 | 0.79 | SLC6A4 (0.51) | NPC1RAB9AL3MBTL1SLC6A4SLC6A3 | |
| SCHEMBL31372850 | 0.79 | NPSR1 (0.38) | NPC1RAB9ARPS6KB1CSNK1DGSK3A | |
| SCHEMBL644695 | 0.78 | NPSR1 (0.43) | NPC1RAB9AALPLL3MBTL1KDM4E | |
| SCHEMBL29738141 | 0.78 | NPSR1 (0.43) | NPC1RAB9AALPLL3MBTL1KDM4E | |
| SCHEMBL30954987 | 0.78 | SRC (0.33) | SRCBTKPDGFRBFGFR1PDGFRA | |
| SCHEMBL14260604 | 0.73 | OPRK1 (0.47) | PDK2NPC1RAB9AL3MBTL1SLC6A4 | |
| SCHEMBL2592299 | 0.73 | AGBL2 (0.47) | NPC1RAB9AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL30960746 | 0.72 | TUBB4A (0.40) | ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108715590-B | Thiazolecarboxamide and picolinamide compounds useful as PIM kinase inhibitors | 因赛特公司 | 2022-03-08 | — | — | CN | disclosed |