Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3083067 | 0.91 | OPRM1 (0.46) | ALDH1A1SMN1; SMN2OPRM1MMP1MMP2 | |
| SCHEMBL3091637 | 0.90 | OPRM1 (0.46) | ALDH1A1SMN1; SMN2OPRM1MMP1MMP2 | |
| SCHEMBL3091429 | 0.89 | HSD17B1 (0.43) | C5AR1OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3083240 | 0.88 | OPRM1 (0.39) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3081588 | 0.88 | SLC6A3 (0.39) | OPRM1SLC6A2SLC6A4SLC6A3MBTPS1 | |
| SCHEMBL3088108 | 0.84 | SLC6A4 (0.41) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3086775 | 0.81 | KMT2A (0.40) | ALDH1A1SMN1; SMN2UTS2RPOLBKMT2A | |
| SCHEMBL3094952 | 0.80 | OPRM1 (0.43) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3101074 | 0.80 | OPRM1 (0.44) | OPRM1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3089729 | 0.79 | OPRM1 (0.43) | ALDH1A1SMN1; SMN2OPRM1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2010-09-16 | — | — | US | claimed |
| EP-1987001-B1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-05-05 | — | — | EP | claimed |
| EP-1987001-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NeuroSearch A/S (DK) | 2008-11-05 | — | — | EP | claimed |
| WO-2007093603-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | WO | claimed |
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2010-09-16 | — | — | US | disclosed |
| EP-1987001-B1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-05-05 | — | — | EP | disclosed |
| EP-1987001-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NeuroSearch A/S (DK) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093603-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | OPRL1, OPRM1, OPRK1 | ALDH1A1 981/4885SMN1; SMN2 2829/4885BCL2A1 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.