Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174612 | 0.85 | F2 (0.41) | L3MBTL1MEN1KMT2AALDH1A1ACHE | |
| SCHEMBL30955773 | 0.83 | L3MBTL1 (0.39) | L3MBTL1MEN1KMT2AALDH1A1ACHE | |
| SCHEMBL1558028 | 0.80 | SIGMAR1 (0.40) | L3MBTL1MEN1KMT2AALDH1A1ACHE | |
| SCHEMBL30955814 | 0.80 | L3MBTL1 (0.34) | L3MBTL1MEN1KMT2AALDH1A1ACHE | |
| SCHEMBL22648279 | 0.80 | SIGMAR1 (0.47) | L3MBTL1MEN1KMT2AALDH1A1ACHE | |
| SCHEMBL16975385 | 0.79 | ACHE (0.45) | L3MBTL1KMT2AALDH1A1ACHEF2 | |
| SCHEMBL16974776 | 0.79 | ACHE (0.42) | L3MBTL1ALDH1A1ACHEF2PLAU | |
| SCHEMBL17199450 | 0.79 | F2 (0.39) | L3MBTL1ALDH1A1ACHEF2PLAU | |
| SCHEMBL18761846 | 0.79 | F2 (0.39) | L3MBTL1ALDH1A1ACHEF2PLAU | |
| SCHEMBL17199452 | 0.79 | F2 (0.39) | L3MBTL1ALDH1A1ACHEF2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638454-A1 | SUBSTITUTED IMIDAZO-BASED COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK3 | Celgene Corporation (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137743-A1 | SUBSTITUTED IMIDAZO-BASED COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK3 | CELGENE CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |