SCHEMBL3095651

SCHEMBL3095651

CC(=O)OCC(CNc1c(I)c(N)c(I)c(NCC(COC(C)=O)OC(C)=O)c1I)OC(C)=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.34
AR P10275 1/20 0.33
GAA P10253 1/20 0.32
PRKCA P17252 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515975 0.78 ABCB1 (0.37) TDP1ARGAA
SCHEMBL1359798 0.78 LMNA (0.38) TDP1ARGAA
SCHEMBL4927394 0.77 LMNA (0.38) TDP1
SCHEMBL8378374 0.77 LMNA (0.34) TDP1
SCHEMBL8377049 0.77 LMNA (0.36) TDP1
SCHEMBL8374414 0.76 LMNA (0.34) TDP1
SCHEMBL28880448 0.76 LMNA (0.36) TDP1AR
SCHEMBL7594178 0.75 TDP1 (0.37) TDP1ARGAAPRKCA
SCHEMBL8764396 0.75 ABCB1 (0.32)
SCHEMBL8063052 0.75 LMNA (0.36) TDP1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1792894-B1 Contrast agents GE HEALTHCARE AS (NO) 2010-09-22 EP disclosed
US-7485753-B2 Contrast agents GE HEALTHCARE AS (NO) 2009-02-03 US disclosed
US-20080199402-A1 Contrast Agents GE HEALTHCARE AS (NO) 2008-08-21 US disclosed
EP-1792894-A2 Contrast agents GE Healthcare AS (NO) 2007-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080199402-A1 Contrast Agents PYM1, MIA3, IPO11 TDP1 2302/4885AR 4022/4885GAA 4385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.