SCHEMBL30957147

SCHEMBL30957147

Cc1c(C#N)cccc1OB(O)O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
NISCH Q9Y2I1 1/20 0.39
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
SSTR4 P31391 1/20 0.37
ALDH1A1 P00352 3/20 0.36
AR P10275 6/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
MAPK1 P28482 1/20 0.34
HPGD P15428 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
MAOA P21397 1/20 0.33
HTR2B P41595 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1372811 0.81 GAA (0.46) TSHRPOLBGAAALDH1A1AR
SCHEMBL30517279 0.81 GAA (0.46) TSHRPOLBGAAALDH1A1AR
SCHEMBL31189733 0.80 TSHR (0.36) TSHRPOLBGAAALDH1A1AR
SCHEMBL31355745 0.80 SMN1; SMN2 (0.38) TSHRPOLBGAAALDH1A1SMN1; SMN2
SCHEMBL4119375 0.77 POLB (0.50) TSHRPOLBGAAALDH1A1AR
SCHEMBL457239 0.77 MAPT (0.47) POLBGAAALDH1A1RAB9A
SCHEMBL30338488 0.77 MAPT (0.47) POLBGAAALDH1A1RAB9A
SCHEMBL22172091 0.76 TSHR (0.43) TSHRNISCHPOLBGAASSTR4
SCHEMBL5636872 0.74 TSHR (0.42) TSHRNISCHPOLBGAASSTR4
SCHEMBL21728172 0.74 ACHE (0.54) TSHRSSTR4ALDH1A1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118660478-A Light emitting device, light emitting apparatus, electronic device, and lighting apparatus 株式会社半导体能源研究所 2024-09-17 CN disclosed
CN-112703616-B Light emitting device, light emitting apparatus, electronic device, and lighting apparatus 株式会社半导体能源研究所 2024-06-28 CN disclosed