Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30517279 | 1.00 | GAA (0.46) | GAAPOLBTSHRSMN1; SMN2MAPK1 | |
| 1,3-Propanediol SCHEMBL28556057 | 0.89 | SMN1; SMN2 (0.39) | GAAPOLBTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL31189733 | 0.82 | TSHR (0.36) | GAAPOLBTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL31355745 | 0.82 | SMN1; SMN2 (0.38) | GAAPOLBTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL30957147 | 0.81 | TSHR (0.44) | GAAPOLBTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL31019102 | 0.79 | FABP7 (0.35) | — | |
| SCHEMBL30441431 | 0.77 | IMPDH2 (0.61) | TSHRAR | |
| SCHEMBL30522390 | 0.77 | AR (0.42) | ALDH1A1HPGDARMAOAKDM4E | |
| SCHEMBL6678412 | 0.77 | ENPP2 (0.44) | GAATSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29706601 | 0.77 | ENPP2 (0.44) | GAATSHRSMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772131-A | Biaryl compound and preparation method and application thereof | 河南大学 | 2024-10-15 | — | — | CN | claimed |
| EP-1506176-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2013-04-24 | — | — | EP | claimed |
| JP-11152269-A | — | — | None | — | — | JP | disclosed |
| CN-117497840-A | Gel electrolyte, preparation method thereof and sodium ion battery | 广东省豪鹏新能源科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-114262330-B | Fascaplysin derivative, preparation method and application thereof in resisting MRSA | 宁波大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-115160217-A | Preparation method of Perampanel, synthetic intermediate and preparation method of degradation impurities | 山东达因海洋生物制药股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-112912047-A | Microneedle array patch with glucose responsive matrix for closed-loop insulin delivery | 北卡罗莱纳州立大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-110028442-B | Simple preparation method of Perampanel | 新发药业有限公司 | 2020-07-17 | — | — | CN | disclosed |
| US-9115136-B2 | Fused ring compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-08-25 | — | — | US | disclosed |
| US-8921379-B2 | Fused ring compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-12-30 | — | — | US | disclosed |
| US-20140046056-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20100197683-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2010-08-05 | — | — | US | disclosed |
| WO-2010087515-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |
| US-20100168070-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | HEINE NIKLAS | 2010-07-01 | — | — | US | disclosed |
| US-20100144681-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM INTERNATION GMNB (DE) | 2010-06-10 | — | — | US | disclosed |
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6281214-B1 | USEFUL FOR TREATING AND AMELIORATING MENTAL DISORDERS | EISAI CO., LTD (JP) | 2001-08-28 | — | — | US | disclosed |
| JP-H11152269-A | BIPHENYLAMINDINE DERIVATIVE | TEIJIN LTD | 1999-06-08 | — | — | JP | disclosed |
| US-5849912-A | Biphenyl derivatives | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0675118-A2 | Biphenylderivatives, process for their preparation and their use as medicaments | Eisai Co., Ltd. (JP) | 1995-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046056-A1 | FUSED RING COMPOUND AND USE THEREOF | PPARA, PPARG, AGTR2 | GAA 1880/4885POLB 2330/4885TSHR 542/4885 |
| US-20100168070-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | PSEN1, PSEN2, ADORA3 | GAA 191/4885POLB 654/4885TSHR 2173/4885 |
| US-20100144681-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | PSEN1, PSEN2, ADORA3 | GAA 207/4885POLB 685/4885TSHR 2133/4885 |
| US-20100197683-A1 | FUSED RING COMPOUND AND USE THEREOF | PPARA, PPARG, AGTR2 | GAA 1880/4885POLB 2330/4885TSHR 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.