Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095771 | 1.00 | EHMT2 (0.43) | EHMT2CYP2C19CYP2C9KMT2AF2 | |
| SCHEMBL3092207 | 0.84 | EHMT2 (0.44) | EHMT2CYP2C19CYP2C9KMT2AF2 | |
| SCHEMBL9736877 | 0.76 | EHMT2 (0.41) | EHMT2KMT2AF2PLGELANE | |
| SCHEMBL9736566 | 0.76 | EHMT2 (0.41) | EHMT2KMT2AF2PLGELANE | |
| SCHEMBL22130803 | 0.75 | EHMT2 (0.56) | EHMT2CYP2C19CYP2C9KMT2AF2 | |
| SCHEMBL353717 | 0.75 | EHMT2 (0.56) | EHMT2CYP2C19CYP2C9KMT2AF2 | |
| SCHEMBL351271 | 0.75 | EHMT2 (0.56) | EHMT2CYP2C19CYP2C9KMT2AF2 | |
| SCHEMBL11174075 | 0.74 | EHMT2 (0.47) | EHMT2CYP2C19CYP2C9KMT2AF2 | |
| SCHEMBL11174081 | 0.74 | EHMT2 (0.47) | EHMT2CYP2C19CYP2C9KMT2AF2 | |
| SCHEMBL11174084 | 0.74 | EHMT2 (0.47) | EHMT2CYP2C19CYP2C9KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799929-B2 | Biotin intermediate and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| EP-1462444-B1 | INTERMEDIATE FOR BIOTIN AND PROCESS FOR PRODUCING THE SAME | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-09-16 | — | — | EP | disclosed |
| EP-2098528-A2 | Biotin intermediate and process for preparing the same | Mitsubishi Tanabe Pharma Corporation (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-20080119655-A1 | Biotin intermediate and process for preparing the same | SEKI MASAHIKO | 2008-05-22 | — | — | US | disclosed |
| US-7335778-B2 | Intermediate for biotin and process for producing the same | TANABE SEIYAKU CO., LTD. (JP) | 2008-02-26 | — | — | US | disclosed |
| US-20050038260-A1 | Intermediate for biotin and process for producing the same | API CORPORATION (JP) | 2005-02-17 | — | — | US | disclosed |
| EP-1462444-A1 | INTERMEDIATE FOR BIOTIN AND PROCESS FOR PRODUCING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119655-A1 | Biotin intermediate and process for preparing the same | BTD, BOLA2; BOLA2B, BCAT1 | EHMT2 308/4885CYP2C19 1325/4885CYP2C9 1193/4885 |
| US-20050038260-A1 | Intermediate for biotin and process for producing the same | BTD, BCAT1, HLCS | EHMT2 388/4885CYP2C19 1208/4885CYP2C9 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.