SCHEMBL3095793

SCHEMBL3095793

Clc1nc(Cl)c(-c2cccc3ccccc23)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
TYMP P19971 1/20 0.44
CYP1A2 P05177 2/20 0.41
CYP2A6 P11509 1/20 0.41
NISCH Q9Y2I1 1/20 0.40
GSK3B P49841 2/20 0.40
CDK5 Q00535 1/20 0.40
CDK5R1 Q15078 1/20 0.40
BCHE P06276 1/20 0.39
KDM4E B2RXH2 4/20 0.38
BRD4 O60885 1/20 0.38
ALPL P05186 1/20 0.38
GAA P10253 1/20 0.38
PARP1 P09874 1/20 0.38
ALDH1A1 P00352 2/20 0.37
ATM Q13315 2/20 0.37
HSD17B10 Q99714 2/20 0.37
PI4KA P42356 1/20 0.37
PI4K2B Q8TCG2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6998276 0.71 NPC1 (0.36) RAB9ANPC1TYMPGSK3BCDK5
SCHEMBL3097526 0.71 KDM4E (0.42) KDM4EGAAALDH1A1HSD17B10MAPK13
SCHEMBL25302086 0.68 ALDH1A1 (0.59) CYP1A2CYP2A6NISCHKDM4EALPL
SCHEMBL27953 0.68 ALDH1A1 (0.59) CYP1A2CYP2A6NISCHKDM4EALPL
SCHEMBL29350007 0.68 ALDH1A1 (0.59) CYP1A2CYP2A6NISCHKDM4EALPL
SCHEMBL3096766 0.68 NISCH (0.40) TYMPNISCHGSK3BCDK5CDK5R1
SCHEMBL3103466 0.68 PDGFRB (0.44) RAB9ANPC1TYMPCYP1A2CYP2A6
SCHEMBL186872 0.67 PI4KA (0.49) RAB9ATYMPCYP1A2CYP2A6NISCH
SCHEMBL6637136 0.67 MAPT (0.50) RAB9ANPC1CYP1A2CYP2A6NISCH
SCHEMBL16107082 0.67 GSK3B (0.56) TYMPNISCHGSK3BBCHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2141151-B1 METHOD FOR PRODUCING 2-HALOIMIDAZOLE COMPOUND SHIKOKU CHEM (JP) 2013-03-20 EP disclosed
EP-2141151-A1 METHOD FOR PRODUCING 2-HALOIMIDAZOLE COMPOUND SHIKOKU CHEMICALS CORPORATION (JP) 2010-01-06 EP disclosed