Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 9/20 | 0.44 |
| ▸ | ANPEP | P15144 | 5/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | IL1RN | P18510 | 2/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095888 | 1.00 | LAP3 (0.44) | LAP3ANPEPERAP1MMP1MMP8 | |
| SCHEMBL2985775 | 0.83 | LAP3 (0.41) | LAP3ANPEPERAP1SLC7A5 | |
| SCHEMBL2985773 | 0.83 | LAP3 (0.41) | LAP3ANPEPERAP1SLC7A5 | |
| SCHEMBL3103343 | 0.79 | FDPS (0.31) | FDPS | |
| SCHEMBL3103350 | 0.79 | FDPS (0.31) | FDPS | |
| SCHEMBL3108107 | 0.78 | FDPS (0.42) | LAP3FDPS | |
| SCHEMBL3108119 | 0.78 | FDPS (0.42) | LAP3FDPS | |
| SCHEMBL3109099 | 0.77 | ENPEP (0.35) | FDPS | |
| SCHEMBL3100554 | 0.77 | CA2 (0.31) | FDPS | |
| SCHEMBL3091959 | 0.77 | CA2 (0.31) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |