Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 4/20 | 0.36 |
| ▸ | TSPO | P30536 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961812 | 0.85 | CAMK2D (0.36) | PTGER4LMNANPSR1TSHRHSD17B10 | |
| SCHEMBL30961757 | 0.84 | MAPT (0.36) | PTGER4TSPOCYP1A2CYP2C19OPRM1 | |
| SCHEMBL30961882 | 0.82 | TSPO (0.35) | TSPOCYP1A2CYP2C19OPRM1LMNA | |
| SCHEMBL31661382 | 0.77 | TSHR (0.40) | PTGER4L3MBTL1ELANENR4A2LMNA | |
| SCHEMBL30961858 | 0.77 | CAMK2D (0.35) | TSHRHSD17B10IDO1ALDH1A1MAPT | |
| SCHEMBL30961808 | 0.76 | MAPT (0.38) | PTGER4LMNANPSR1TSHRHSD17B10 | |
| SCHEMBL30961813 | 0.75 | CAMK2D (0.36) | PTGER4LMNAPLA2G2AHSD17B10METAP2 | |
| SCHEMBL31661333 | 0.72 | PTGER4 (0.38) | PTGER4L3MBTL1HTTTSHRHSD17B10 | |
| SCHEMBL31661358 | 0.71 | IDO1 (0.38) | PTGER4HTTTSHRIDO1METAP2 | |
| SCHEMBL30961771 | 0.69 | NT5E (0.35) | TSPOLMNAHTTNPSR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4633739-A1 | COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | Flare Therapeutics, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024129715-A1 | COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2024-06-20 | — | — | WO | disclosed |