Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 5/20 | 0.37 |
| ▸ | METAP2 | P50579 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661358 | 0.91 | IDO1 (0.38) | PTGER4IDO1METAP2TSHRHTT | |
| SCHEMBL31661382 | 0.91 | TSHR (0.40) | PTGER4IDO1METAP2TSHRHTT | |
| SCHEMBL31661401 | 0.85 | METAP2 (0.35) | PTGER4METAP2TSHRHSD17B10 | |
| SCHEMBL31661317 | 0.78 | LMNA (0.45) | METAP2HTTHSD17B10 | |
| SCHEMBL31661335 | 0.78 | PTGER4 (0.38) | PTGER4METAP2 | |
| SCHEMBL31661377 | 0.77 | METAP2 (0.38) | PTGER4METAP2HSD17B10EGFRL3MBTL1 | |
| SCHEMBL31661400 | 0.77 | PARP1 (0.38) | METAP2 | |
| SCHEMBL30961817 | 0.72 | PTGER4 (0.38) | PTGER4IDO1METAP2TSHRHTT | |
| SCHEMBL31661339 | 0.71 | CAMK2D (0.37) | METAP2HTTPPARG | |
| SCHEMBL30961882 | 0.70 | TSPO (0.35) | IDO1METAP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |