Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 4/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661333 | 0.91 | PTGER4 (0.38) | TSHRHTTMETAP2PTGER4L3MBTL1 | |
| SCHEMBL31661358 | 0.90 | IDO1 (0.38) | TSHRHTTMETAP2PTGER4IDO1 | |
| SCHEMBL31661377 | 0.86 | METAP2 (0.38) | METAP2PTGER4L3MBTL1MAPK1HSD17B10 | |
| SCHEMBL31661317 | 0.79 | LMNA (0.45) | HTTMETAP2ELANELMNAMAPK1 | |
| SCHEMBL30961817 | 0.77 | PTGER4 (0.38) | TSHRHTTMETAP2PTGER4L3MBTL1 | |
| SCHEMBL31661401 | 0.77 | METAP2 (0.35) | TSHRMETAP2PTGER4HSD17B10 | |
| SCHEMBL31661335 | 0.77 | PTGER4 (0.38) | METAP2PTGER4 | |
| SCHEMBL31661400 | 0.76 | PARP1 (0.38) | METAP2 | |
| SCHEMBL30961757 | 0.72 | MAPT (0.36) | TSHRHTTMETAP2PTGER4IDO1 | |
| SCHEMBL30961882 | 0.69 | TSPO (0.35) | HTTMETAP2IDO1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |