Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ATF1 | P18846 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962730 | 0.93 | POLB (0.46) | CHRNA7MEN1KMT2AMAPTKEAP1 | |
| SCHEMBL16649261 | 0.88 | PIN1 (0.50) | CHRNA7MEN1KMT2AMAPTKEAP1 | |
| SCHEMBL30962582 | 0.87 | CHRNA7 (0.41) | CHRNA7MEN1KMT2AMAPTKEAP1 | |
| SCHEMBL30962627 | 0.86 | PDE4A (0.43) | CHRNA7MEN1KMT2AMAPTKEAP1 | |
| SCHEMBL30962881 | 0.85 | NFKB1 (0.48) | PDE4DPDE4APDE4BPDE4CATF1 | |
| SCHEMBL30962815 | 0.85 | CHRNA7 (0.40) | CHRNA7MEN1KMT2AMAPTKEAP1 | |
| SCHEMBL31612072 | 0.84 | TYRO3 (0.48) | CHRNA7MEN1KMT2AMAPTKEAP1 | |
| SCHEMBL29076206 | 0.84 | TYRO3 (0.48) | CHRNA7MEN1KMT2AMAPTKEAP1 | |
| SCHEMBL30962863 | 0.83 | NFKB1 (0.42) | MEN1KMT2AMAPTPDE4DPDE4A | |
| SCHEMBL31612059 | 0.82 | LCK (0.46) | CHRNA7MEN1KMT2AMAPTKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |