Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 14/20 | 0.75 |
| ▸ | MAOB | P27338 | 14/20 | 0.75 |
| ▸ | DRD2 | P14416 | 5/20 | 0.72 |
| ▸ | HTR6 | P50406 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066640 | 0.97 | MAOA (0.71) | MAOAMAOBDRD2HTR6 | |
| Hydrochloric Acid SCHEMBL11068783 | 0.96 | MAOA (0.70) | MAOAMAOBDRD2HTR6 | |
| SCHEMBL11062872 | 0.89 | KDM1A (0.66) | MAOAMAOBDRD2 | |
| SCHEMBL11074474 | 0.87 | MAOA (0.68) | MAOAMAOBDRD2 | |
| SCHEMBL11066832 | 0.87 | MAOA (0.68) | MAOAMAOBDRD2 | |
| SCHEMBL11066861 | 0.87 | DRD2 (0.69) | MAOAMAOBDRD2HTR6 | |
| SCHEMBL11064535 | 0.86 | MAOA (0.64) | MAOAMAOBDRD2 | |
| SCHEMBL11062856 | 0.85 | MAOA (1.00) | MAOAMAOBDRD2HTR6 | |
| SCHEMBL11066390 | 0.85 | MAOA (1.00) | MAOAMAOBDRD2HTR6 | |
| SCHEMBL10665990 | 0.84 | DRD2 (1.00) | MAOAMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |