Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964916 | 0.84 | NR1H4 (0.47) | NR1H4CYP4F2CYP4A11RXRAHPGD | |
| SCHEMBL24410145 | 0.83 | ALDH1A1 (0.51) | ALDH1A1GAAGFERSMN1; SMN2NPC1 | |
| SCHEMBL1786183 | 0.82 | NPC1 (0.63) | ALDH1A1GAAGFERSMN1; SMN2NPC1 | |
| SCHEMBL30965013 | 0.82 | SRD5A2 (0.57) | ALDH1A1GAANR1H4SRD5A2RXRA | |
| SCHEMBL14239394 | 0.82 | ALDH1A1 (0.67) | ALDH1A1GAAGFERSMN1; SMN2NPC1 | |
| SCHEMBL11009620 | 0.81 | NR1H4 (0.49) | ALDH1A1NR1H4CYP4F2CYP4A11SRD5A2 | |
| SCHEMBL12960365 | 0.79 | RXRA (0.53) | NR1H4CYP4F2CYP4A11SRD5A2RXRA | |
| SCHEMBL2127019 | 0.79 | GAA (0.68) | ALDH1A1GAAGFERSMN1; SMN2NPC1 | |
| SCHEMBL12062913 | 0.79 | ALDH1A1 (0.54) | ALDH1A1GAAGFERSMN1; SMN2NPC1 | |
| SCHEMBL30096935 | 0.79 | GAA (0.68) | ALDH1A1GAAGFERSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121779-A1 | PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS | PFIZER INC. (US) | 2024-06-13 | — | — | WO | disclosed |