Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 3/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965253 | 0.90 | WDR5 (0.43) | WDR5PIK3CDMETAP2MAPTALDH1A1 | |
| SCHEMBL30965264 | 0.90 | ACLY (0.44) | WDR5PIK3CDMETAP2MAPTALDH1A1 | |
| SCHEMBL30965244 | 0.87 | CYP19A1 (0.47) | ALDH1A1KMT2AS1PR3 | |
| SCHEMBL30965268 | 0.83 | ALDH1A1 (0.44) | MAPTALDH1A1NPSR1BRD4SMN1; SMN2 | |
| SCHEMBL30965202 | 0.80 | TDP1 (0.40) | ALDH1A1SMN1; SMN2KMT2ACA12CA9 | |
| SCHEMBL30965207 | 0.80 | MCL1 (0.41) | METAP2MAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL30965224 | 0.79 | CYP19A1 (0.45) | ALDH1A1KMT2ACA12CA9 | |
| SCHEMBL30965153 | 0.77 | CYP19A1 (0.46) | MAPTALDH1A1NPSR1SMN1; SMN2S1PR3 | |
| SCHEMBL30965179 | 0.76 | CYP19A1 (0.45) | ALDH1A1NPSR1SMN1; SMN2KMT2AS1PR3 | |
| SCHEMBL30965219 | 0.75 | TDP1 (0.43) | MAPTALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125964-A | Isoindoline-1, 3-diketone mPGES-1 inhibitor and application thereof | 长江大学 | 2024-06-04 | — | — | CN | disclosed |