Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.38 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965792 | 0.88 | CRBN (0.41) | CRBNDDB1FFAR4AR | |
| SCHEMBL30965621 | 0.87 | CHRM4 (0.39) | CRBNDDB1ENPP2ATXN2CHRM4 | |
| SCHEMBL30965580 | 0.86 | CHRM4 (0.43) | CA1CA2ACHECRBNDDB1 | |
| SCHEMBL31487487 | 0.85 | CCR3 (0.38) | CRBNDDB1ARKMT2A | |
| SCHEMBL30965796 | 0.84 | ACHE (0.41) | CA1CA2ACHESMPD3FFAR4 | |
| SCHEMBL31487522 | 0.84 | CRBN (0.39) | CRBNDDB1FFAR4AROPRK1 | |
| SCHEMBL30965534 | 0.83 | CRBN (0.43) | ACHECRBNDDB1FFAR4 | |
| SCHEMBL30965622 | 0.83 | ENPP2 (0.37) | CRBNDDB1ENPP2ATXN2AR | |
| SCHEMBL30965750 | 0.83 | POLB (0.42) | CA1CA2ACHESMPD3FFAR4 | |
| SCHEMBL30965684 | 0.82 | DRD2 (0.39) | CRBNDDB1FFAR4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |