SCHEMBL30965684

SCHEMBL30965684

CC(C)(C)OC(=O)NC1CC2(CCN(CC3CCN(c4cc(F)c(NC5CCC(=O)NC5=O)cc4F)CC3)CC2)C1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.39
CRBN Q96SW2 13/20 0.38
DDB1 Q16531 11/20 0.38
AR P10275 1/20 0.34
GAA P10253 1/20 0.33
F10 P00742 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30965792 0.94 CRBN (0.41) DRD2CRBNDDB1ARFFAR4
SCHEMBL30965660 0.93 DRD2 (0.40) DRD2CRBNDDB1
SCHEMBL25024163 0.91 CRBN (0.43) DRD2CRBNDDB1F10
SCHEMBL30135765 0.91 CRBN (0.43) DRD2CRBNDDB1F10
SCHEMBL30135859 0.88 CRBN (0.41) DRD2CRBNDDB1
SCHEMBL30965669 0.85 CRBN (0.43) DRD2CRBNDDB1
SCHEMBL30965799 0.85 DRD2 (0.44) DRD2CRBNDDB1
SCHEMBL25024152 0.84 CRBN (0.47) DRD2CRBNDDB1AR
SCHEMBL31487523 0.84 CRBN (0.40) CRBNDDB1ARFFAR4
SCHEMBL30965761 0.83 CRBN (0.40) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658658-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND Uppthera, Inc. (KR) 2025-12-10 EP disclosed
WO-2024162828-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND UPPTHERA, INC. (KR) 2024-08-08 WO disclosed