Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965686 | 0.90 | CHRM4 (0.53) | CHRM4HTR1ADRD2HTR2ATSHR | |
| SCHEMBL30965749 | 0.88 | CHRM4 (0.50) | CHRM4HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL30965830 | 0.87 | CHRM4 (0.49) | CHRM4HTR1ADRD2HTR2ATSHR | |
| SCHEMBL30135849 | 0.86 | CTSL (0.48) | CHRM4HTR1ADRD2HTR2ATSHR | |
| SCHEMBL31335045 | 0.85 | TSHR (0.48) | CHRM4TSHRALDH1A1GAACTSL | |
| SCHEMBL30965560 | 0.85 | CHRM4 (0.59) | CHRM4HTR1ADRD2HTR2ATSHR | |
| SCHEMBL30965559 | 0.85 | CHRM4 (0.51) | CHRM4HTR1ADRD2HTR2ATSHR | |
| SCHEMBL31712335 | 0.84 | DRD2 (0.54) | CHRM4HTR1ADRD2HTR2A | |
| SCHEMBL30135895 | 0.82 | CTSL (0.41) | CHRM4TSHRALDH1A1GAACTSL | |
| SCHEMBL30965538 | 0.82 | CHRM4 (0.45) | CHRM4HTR1ADRD2HTR2ATGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |