Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965686 | 0.91 | CHRM4 (0.53) | CHRM4DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL30965635 | 0.89 | CHRM4 (0.48) | CHRM4DRD2HTR1AHTR2AACHE | |
| SCHEMBL30965733 | 0.87 | CHRM4 (0.54) | CHRM4DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL30965796 | 0.83 | ACHE (0.41) | CHRM4DRD2HTR2AACHECA1 | |
| SCHEMBL30965580 | 0.83 | CHRM4 (0.43) | CHRM4DRD2HTR1AHTR2AACHE | |
| SCHEMBL30965560 | 0.83 | CHRM4 (0.59) | CHRM4DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL30965559 | 0.82 | CHRM4 (0.51) | CHRM4DRD2HTR1AHTR2AACHE | |
| SCHEMBL30965716 | 0.82 | HTR1A (0.45) | CHRM4DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL30965749 | 0.80 | CHRM4 (0.50) | CHRM4DRD2HTR1AHTR2AACHE | |
| SCHEMBL30965540 | 0.76 | DRD2 (0.58) | CHRM4DRD2HTR1AHTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |