Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965765 | 0.91 | MAPT (0.44) | CHRM4DRD2HTR1AHTR2AMAPT | |
| SCHEMBL30965559 | 0.89 | CHRM4 (0.51) | CHRM4DRD2HTR1AHTR2ASIGMAR1 | |
| SCHEMBL30135904 | 0.88 | SIGMAR1 (0.47) | CHRM4MAPTSIGMAR1POLBALDH1A1 | |
| SCHEMBL30965733 | 0.88 | CHRM4 (0.54) | CHRM4DRD2HTR1AHTR2AF13A1 | |
| SCHEMBL31334781 | 0.87 | MAPT (0.46) | MAPTSIGMAR1POLBF13A1TGM2 | |
| SCHEMBL30965635 | 0.87 | CHRM4 (0.48) | CHRM4DRD2HTR1AHTR2AMAPT | |
| SCHEMBL30135712 | 0.83 | MAPT (0.45) | CHRM4MAPTSIGMAR1POLBALDH1A1 | |
| SCHEMBL30965686 | 0.83 | CHRM4 (0.53) | CHRM4DRD2HTR1AHTR2AF13A1 | |
| SCHEMBL30965693 | 0.81 | HTR1A (0.44) | CHRM4DRD2HTR1AHTR2AACHE | |
| SCHEMBL30965560 | 0.80 | CHRM4 (0.59) | CHRM4DRD2HTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |