Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | STK17B | O94768 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967451 | 0.86 | PARP1 (0.36) | CKS1BSKP1SKP2BCHESSTR4 | |
| SCHEMBL31751652 | 0.76 | SMN1; SMN2 (0.44) | ATRBCHEPARP1KDM4EPOLB | |
| SCHEMBL30967478 | 0.68 | CYP1A2 (0.44) | ATRDYRK1AKDM4E | |
| SCHEMBL20500778 | 0.66 | TDP1 (0.54) | CKS1BSKP1SKP2TDP1IDO1 | |
| SCHEMBL6753294 | 0.66 | TDP1 (0.54) | CKS1BSKP1SKP2SSTR4STK17B | |
| SCHEMBL6988118 | 0.66 | TACR1 (0.51) | CKS1BSKP1SKP2 | |
| SCHEMBL24112892 | 0.65 | NUDT1 (0.52) | ROCK2ROCK1CCNCCDK8KDM4E | |
| SCHEMBL25758891 | 0.65 | ALOX15 (0.54) | ROCK2ROCK1DYRK1ACCNCCDK8 | |
| SCHEMBL30189256 | 0.65 | GRIN1 (0.50) | CCNCCDK8KDM4E | |
| SCHEMBL24113095 | 0.65 | GRIN1 (0.50) | CCNCCDK8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |