Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968035 | 1.00 | CHRM4 (0.36) | CHRM4PTAFRHRH3CCR5GPR142 | |
| SCHEMBL30968010 | 1.00 | CHRM4 (0.36) | CHRM4PTAFRHRH3CCR5GPR142 | |
| SCHEMBL30968122 | 0.85 | WNK1 (0.33) | CHRM4PTAFRCCR5PTGDR2WNK1 | |
| SCHEMBL30968142 | 0.83 | USP30 (0.38) | CHRM4PTAFRHRH3CCR5USP30 | |
| SCHEMBL31065803 | 0.83 | USP30 (0.38) | CHRM4PTAFRHRH3CCR5USP30 | |
| SCHEMBL30968100 | 0.83 | PTAFR (0.35) | CHRM4PTAFRHRH3GPR142PTGDR2 | |
| SCHEMBL30968042 | 0.83 | PTAFR (0.35) | CHRM4PTAFRHRH3GPR142PTGDR2 | |
| SCHEMBL30968132 | 0.83 | PTAFR (0.35) | CHRM4PTAFRHRH3GPR142PTGDR2 | |
| SCHEMBL30968089 | 0.78 | PARP1 (0.33) | PTAFRHRH3GPR142 | |
| SCHEMBL30968069 | 0.77 | MAPK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |