Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 6/20 | 0.32 |
| ▸ | HTR3B | O95264 | 6/20 | 0.32 |
| ▸ | HTR3A | P46098 | 6/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 6/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 6/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968035 | 0.85 | CHRM4 (0.36) | WNK1PTGDR2CHRM4CCR5PTAFR | |
| SCHEMBL30967959 | 0.85 | CHRM4 (0.36) | WNK1PTGDR2CHRM4CCR5PTAFR | |
| SCHEMBL30968010 | 0.85 | CHRM4 (0.36) | WNK1PTGDR2CHRM4CCR5PTAFR | |
| SCHEMBL30967993 | 0.78 | ALOX15 (0.36) | WNK1HPGDTSHR | |
| SCHEMBL30968098 | 0.78 | ALOX15 (0.36) | WNK1HPGDTSHR | |
| SCHEMBL31065803 | 0.68 | USP30 (0.38) | CHRM4CCR5KMT2APTAFR | |
| SCHEMBL30968142 | 0.68 | USP30 (0.38) | CHRM4CCR5KMT2APTAFR | |
| SCHEMBL30968100 | 0.67 | PTAFR (0.35) | PTGDR2CHRM4KMT2APTAFR | |
| SCHEMBL30968042 | 0.67 | PTAFR (0.35) | PTGDR2CHRM4KMT2APTAFR | |
| SCHEMBL30968132 | 0.67 | PTAFR (0.35) | PTGDR2CHRM4KMT2APTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |