Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065774 | 1.00 | GPR119 (0.36) | GPR119KCNK3KCNK9USP30FNTA | |
| SCHEMBL31065803 | 0.89 | USP30 (0.38) | GPR119USP30SUV39H2 | |
| SCHEMBL30968142 | 0.89 | USP30 (0.38) | GPR119USP30SUV39H2 | |
| SCHEMBL30968105 | 0.83 | POLB (0.32) | — | |
| SCHEMBL30968109 | 0.82 | USP30 (0.39) | GPR119USP30SUV39H2 | |
| SCHEMBL31065785 | 0.82 | USP30 (0.39) | GPR119USP30SUV39H2 | |
| SCHEMBL31065776 | 0.77 | GPR119 (0.32) | GPR119USP30 | |
| SCHEMBL30967972 | 0.76 | DHODH (0.37) | — | |
| SCHEMBL30968008 | 0.76 | GPR119 (0.34) | GPR119USP30SUV39H2AURKACDK2 | |
| SCHEMBL30968073 | 0.76 | GPR119 (0.34) | GPR119USP30SUV39H2AURKACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |