Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.34 |
| ▸ | AURKA | O14965 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.32 |
| ▸ | TTK | P33981 | 3/20 | 0.32 |
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968073 | 1.00 | GPR119 (0.34) | GPR119AURKACDK2SPRUSP30 | |
| SCHEMBL30968072 | 0.84 | GPR142 (0.36) | SPRGPR142 | |
| SCHEMBL30968085 | 0.78 | SLC22A12 (0.40) | — | |
| SCHEMBL31065803 | 0.76 | USP30 (0.38) | GPR119SPRUSP30SUV39H2 | |
| SCHEMBL30968142 | 0.76 | USP30 (0.38) | GPR119SPRUSP30SUV39H2 | |
| SCHEMBL30968006 | 0.76 | GPR119 (0.36) | GPR119AURKACDK2USP30SUV39H2 | |
| SCHEMBL31065774 | 0.76 | GPR119 (0.36) | GPR119AURKACDK2USP30SUV39H2 | |
| SCHEMBL31065785 | 0.75 | USP30 (0.39) | GPR119USP30SUV39H2 | |
| SCHEMBL30968109 | 0.75 | USP30 (0.39) | GPR119USP30SUV39H2 | |
| SCHEMBL30968064 | 0.69 | CHRM1 (0.43) | GPR119USP30HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |