Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100630 | 0.85 | PTGS2 (0.39) | THRBCSNK1DPTGS2MAPK14 | |
| SCHEMBL3100615 | 0.84 | CSNK1D (0.44) | THRBTGFBR1CSNK1DPTGS2MAPK14 | |
| SCHEMBL10290371 | 0.83 | THRB (0.52) | THRBTGFBR1CSNK1DMAPK14ACVR1 | |
| SCHEMBL3110918 | 0.83 | THRB (0.54) | THRBTGFBR1CSNK1DMAPK14ACVR1 | |
| SCHEMBL3104990 | 0.81 | THRB (0.51) | THRBTGFBR1CSNK1DMAPK14 | |
| SCHEMBL10290368 | 0.81 | CSNK1D (0.53) | THRBTGFBR1CSNK1DMAPK14ACVR1 | |
| SCHEMBL10290857 | 0.80 | THRB (0.56) | THRBTGFBR1CSNK1DMAPK14 | |
| SCHEMBL3094572 | 0.80 | MAPK14 (0.52) | THRBTGFBR1CSNK1DMAPK14ACVR1 | |
| SCHEMBL3102458 | 0.79 | CSNK1D (0.49) | THRBTGFBR1CSNK1DMAPK14ACVR1 | |
| SCHEMBL10290363 | 0.79 | CSNK1D (0.51) | THRBTGFBR1CSNK1DMAPK14ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217600-B1 | FUNGICIDAL BICYCLIC PYRAZOLES | DU PONT (US) | 2012-12-05 | — | — | EP | claimed |
| EP-2217600-B1 | FUNGICIDAL BICYCLIC PYRAZOLES | DU PONT (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8288375-B2 | Fungicidal bicyclic pyrazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-16 | — | — | US | disclosed |
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | CYP1B1, CBR1, CYP1A1 | THRB 4120/4885TGFBR1 1459/4885CSNK1D 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.