SCHEMBL3100615

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3096838	0.84	THRB (0.48)	CSNK1DPTGS2THRBMAPK14TGFBR1
	SCHEMBL3100630	0.83	PTGS2 (0.39)	CSNK1DPTGS2THRBMAPK14
	SCHEMBL3107458	0.82	MAPK14 (0.47)	CSNK1DTHRBMAPK14TGFBR1MAPK13
	SCHEMBL3102415	0.80	MAPK14 (0.52)	CSNK1DMAPK14MAPK13MAPK12MAPK11
	SCHEMBL2410945	0.72	RAB9A (0.56)	PTGS2TGFBR1KDM4EMITFALDH1A1
	SCHEMBL14593063	0.71	GSK3B (0.55)	PTGS2MAPK14
	SCHEMBL4679983	0.71	MAPK10 (0.43)	PTGS2MAPK14MAPK13MAPK12MAPK11
	SCHEMBL2525132	0.69	HTR3A (0.37)	CSNK1DTHRBMAPK14TGFBR1ALDH1A1
	SCHEMBL5382328	0.69	MAPK14 (0.58)	CSNK1DPTGS2MAPK14KDM4EMITF
	SCHEMBL4677531	0.68	PTGS2 (0.46)	CSNK1DPTGS2MAPK14MAPK11KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.