Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722487 | 1.00 | GPR119 (0.39) | GPR119JAK1JAK2TYK2JAK3 | |
| SCHEMBL20722761 | 0.94 | JAK1 (0.40) | GPR119JAK1JAK2TYK2JAK3 | |
| SCHEMBL30968410 | 0.94 | JAK1 (0.40) | GPR119JAK1JAK2TYK2JAK3 | |
| SCHEMBL20722587 | 0.86 | PPOX (0.32) | — | |
| SCHEMBL20722734 | 0.82 | HSD11B1 (0.43) | GPR119JAK1JAK2TYK2JAK3 | |
| SCHEMBL30968485 | 0.82 | HSD11B1 (0.43) | GPR119JAK1JAK2TYK2JAK3 | |
| SCHEMBL21685920 | 0.79 | PPOX (0.33) | — | |
| SCHEMBL24595748 | 0.76 | CHRM2 (0.42) | GPR119JAK1JAK2TYK2JAK3 | |
| SCHEMBL21457826 | 0.71 | DPP4 (0.42) | GPR119JAK1JAK2TYK2JAK3 | |
| SCHEMBL29577284 | 0.71 | DPP4 (0.42) | GPR119JAK1JAK2TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |