Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722734 | 1.00 | HSD11B1 (0.43) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL20722773 | 0.83 | — | — | |
| SCHEMBL20722487 | 0.82 | GPR119 (0.39) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL30968412 | 0.82 | GPR119 (0.39) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL15065812 | 0.80 | ALDH1A1 (0.46) | GPR119 | |
| SCHEMBL30826616 | 0.80 | ALDH1A1 (0.46) | GPR119 | |
| SCHEMBL24595748 | 0.78 | CHRM2 (0.42) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL21457806 | 0.78 | JAK1 (0.45) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL29577611 | 0.78 | JAK1 (0.45) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL20722761 | 0.77 | JAK1 (0.40) | HSD11B1CHRM2CHRM1CHRM3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |