Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.68 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722588 | 1.00 | NNMT (0.68) | NNMTPIK3C3CYP11B2MAPK1ATM | |
| SCHEMBL21772832 | 0.96 | NNMT (0.62) | NNMTPIK3C3CYP11B2MAPK1ATM | |
| SCHEMBL13332908 | 0.91 | NNMT (0.66) | NNMTPIK3C3MAPK1ATMKDM4E | |
| SCHEMBL16196125 | 0.86 | CYP11B2 (0.57) | NNMTPIK3C3CYP11B2ATM | |
| SCHEMBL22226923 | 0.85 | NNMT (0.63) | NNMTMAPK1KDM4EALDH1A1GAA | |
| SCHEMBL5306512 | 0.82 | NNMT (0.75) | NNMTPIK3C3KDM4EMAPTOGA | |
| SCHEMBL22226925 | 0.81 | NNMT (0.58) | NNMTKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL25787747 | 0.81 | NNMT (1.00) | NNMTPIK3C3CYP11B2KDM4EMAPT | |
| SCHEMBL22225953 | 0.80 | NNMT (0.43) | NNMTMAPK1ATMKDM4EL3MBTL1 | |
| SCHEMBL15878795 | 0.79 | GRM5 (0.45) | NNMTMAPK1ATMKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |