Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 9/20 | 0.78 |
| ▸ | PSMB5 | P28074 | 9/20 | 0.78 |
| ▸ | PSMB2 | P49721 | 7/20 | 0.78 |
| ▸ | LTA4H | P09960 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026592 | 0.98 | PSMB1 (0.75) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL30969243 | 0.96 | PSMB1 (0.72) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL2002718 | 0.93 | HRH3 (0.72) | PSMB1PSMB5PSMB2KDM4EHRH3 | |
| SCHEMBL30969209 | 0.88 | HRH3 (0.66) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL30969213 | 0.87 | DRD3 (0.59) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL1027972 | 0.86 | PSMB1 (0.80) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL2741667 | 0.86 | PSMB1 (0.80) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL6597214 | 0.86 | PSMB1 (0.97) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL3007594 | 0.85 | GAA (0.71) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL30969262 | 0.85 | HRH3 (0.65) | PSMB1PSMB5PSMB2LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | University of Florida Research Fooundation, Incorporated (US) | 2024-07-25 | — | — | US | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | IL6, IL6ST, IL36G | PSMB1 3699/4885PSMB5 3347/4885PSMB2 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.