Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.65 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.58 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026592 | 0.87 | PSMB1 (0.75) | HRH3PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL30969263 | 0.85 | PSMB1 (0.78) | HRH3PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL30969245 | 0.84 | HRH3 (0.56) | HRH3PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL5779141 | 0.83 | SIGMAR1 (0.63) | HRH3KDM4E | |
| SCHEMBL14287744 | 0.83 | L3MBTL3 (0.67) | HRH3PSMB1PSMB5PSMB2KDM4E | |
| Hydrochloric Acid SCHEMBL3859178 | 0.82 | SIGMAR1 (0.65) | HRH3KDM4E | |
| SCHEMBL30969243 | 0.82 | PSMB1 (0.72) | HRH3PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL30969292 | 0.80 | HRH3 (0.54) | HRH3PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL182828 | 0.80 | HRH3 (0.72) | HRH3LTA4H | |
| SCHEMBL2002718 | 0.79 | HRH3 (0.72) | HRH3PSMB1PSMB5PSMB2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |