Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22048752 | 0.82 | HRH3 (0.62) | HRH3PARP10TBXAS1SMN1; SMN2PSMB1 | |
| SCHEMBL1978047 | 0.82 | HRH3 (0.78) | HRH3PARP10TBXAS1SMN1; SMN2PSMB1 | |
| SCHEMBL3827146 | 0.82 | HRH3 (0.70) | HRH3PARP10TBXAS1SMN1; SMN2PSMB1 | |
| SCHEMBL30969254 | 0.80 | HRH3 (0.88) | HRH3PARP10TBXAS1PSMB1PSMB5 | |
| SCHEMBL3007594 | 0.80 | GAA (0.71) | HRH3SMN1; SMN2GAAPSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL14742324 | 0.78 | GAA (0.70) | HRH3SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL3026592 | 0.77 | PSMB1 (0.75) | HRH3PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL18763407 | 0.76 | LTA4H (0.48) | HRH3HRH2HRH1LTA4HCA12 | |
| SCHEMBL30969263 | 0.76 | PSMB1 (0.78) | HRH3PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL3828655 | 0.76 | HRH3 (0.81) | HRH3PARP10TBXAS1PARP15PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |