SCHEMBL30969487

SCHEMBL30969487

Clc1nc(Cl)c2nccc(Cl)c2n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.37
P2RX7 Q99572 2/20 0.33
CCR1 P32246 2/20 0.33
CCR8 P51685 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 4/20 0.33
TDP1 Q9NUW8 4/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
LMNA P02545 3/20 0.32
TP53 P04637 3/20 0.32
HSP90AA1 P07900 3/20 0.32
CYP3A4 P08684 3/20 0.32
MAPT P10636 3/20 0.32
ALOX15 P16050 3/20 0.32
HTT P42858 3/20 0.32
MMP14 P50281 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
MMP9 P14780 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27294793 1.00 NR4A2 (0.37) NR4A2P2RX7CCR1CCR8L3MBTL1
SCHEMBL31685035 0.79 METAP2 (0.39) P2RX7L3MBTL1ALDH1A1KDM4ETDP1
SCHEMBL21899162 0.79 CCR1 (0.43) CCR1CCR8L3MBTL1ALDH1A1LMNA
SCHEMBL27296685 0.79 METAP2 (0.39) P2RX7L3MBTL1ALDH1A1KDM4ETDP1
SCHEMBL25244640 0.79
SCHEMBL7014902 0.75 NR4A2 (0.48) NR4A2CCR1CCR8L3MBTL1ALDH1A1
SCHEMBL21855460 0.75 NQO2 (0.40) L3MBTL1ALDH1A1KDM4EMEN1KMT2A
SCHEMBL21899425 0.75 P2RX7 (0.31) P2RX7
SCHEMBL21196198 0.70 LMNA (0.41) LMNACYP3A4MAPTMAPK1METAP1
SCHEMBL1323446 0.69 ALDH1A1 (0.50) ALDH1A1ALOX15CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117942786-A Preparation method of nanofiltration membrane and nanofiltration membrane prepared by same 沃顿科技股份有限公司 2024-04-30 CN disclosed