Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 4/20 | 0.37 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097239 | 1.00 | ENPEP (0.37) | ENPEPLAP3ALDH1A1MMP1MMP2 | |
| SCHEMBL2991878 | 0.85 | ALDH1A1 (0.50) | ENPEPALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL2991880 | 0.85 | ALDH1A1 (0.50) | ENPEPALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL3100524 | 0.83 | LAP3 (0.37) | LAP3ALDH1A1MMP1MMP2METAP1 | |
| SCHEMBL3100531 | 0.83 | LAP3 (0.37) | LAP3ALDH1A1MMP1MMP2METAP1 | |
| SCHEMBL3102891 | 0.81 | ANPEP (0.32) | LAP3ALDH1A1MMP1MMP8ANPEP | |
| SCHEMBL3102882 | 0.81 | ANPEP (0.32) | LAP3ALDH1A1MMP1MMP8ANPEP | |
| SCHEMBL3102486 | 0.80 | FPR2 (0.44) | ENPEPALDH1A1CA2CA1CA12 | |
| SCHEMBL30700134 | 0.79 | ALDH1A1 (0.41) | ENPEPALDH1A1CA2CA1L3MBTL1 | |
| SCHEMBL7273942 | 0.76 | ENPEP (0.39) | ENPEPALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |