Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 11/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 4/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817711 | 0.81 | RAB9A (0.55) | POLBMAPTHTT | |
| SCHEMBL31377519 | 0.74 | VCP (0.54) | — | |
| SCHEMBL29892765 | 0.73 | KMT2A (0.53) | POLBMAPTHTTGAA | |
| SCHEMBL7979756 | 0.72 | TP53 (0.51) | MAP2K1MAP2K2PRKCZIARS2TP53 | |
| SCHEMBL9542710 | 0.72 | MAPT (0.48) | TP53MAPTGAA | |
| SCHEMBL31485290 | 0.72 | MAP2K1 (0.53) | MAP2K1MAP2K2POLBMAPTHTT | |
| SCHEMBL15771675 | 0.72 | XPO1 (0.41) | POLBRXFP1HTT | |
| SCHEMBL20741611 | 0.71 | HTT (0.51) | MAP2K1MAP2K2HTTGAA | |
| SCHEMBL1419646 | 0.71 | KIF11 (0.57) | MAP2K1MAP2K2HTT | |
| SCHEMBL2650449 | 0.71 | HDAC1 (0.58) | MAP2K1MAP2K2POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359617-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-118359604-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |