Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121472 | 0.84 | HTR3E (0.45) | CUL4AALDH1A1KDM4EHPGDIKBKB | |
| SCHEMBL13077027 | 0.84 | IKBKB (0.66) | ALDH1A1KDM4EGAAPOLBPTPN1 | |
| SCHEMBL25824093 | 0.84 | IKBKB (0.45) | CUL4AALDH1A1KDM4EGAAGLA | |
| SCHEMBL30973203 | 0.84 | IKBKB (0.45) | CUL4AALDH1A1KDM4EGAAGLA | |
| SCHEMBL24832295 | 0.84 | IKBKB (0.45) | CUL4AALDH1A1KDM4EGAAGLA | |
| SCHEMBL17895298 | 0.81 | IKBKB (0.42) | IKBKBPDE2APDE10ACYP1A2CYP2C9 | |
| SCHEMBL8118650 | 0.80 | GRIN2D (0.49) | ALDH1A1KDM4EGAAGLAPOLB | |
| SCHEMBL120846 | 0.80 | MAPK8 (0.54) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL30578099 | 0.80 | MAPK8 (0.54) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL119071 | 0.77 | HTR3E (0.39) | ALDH1A1KDM4EPOLBHPGDIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124287-A | TREATING DEPRESSION | BIOMEDICA FOSCAMA INDUSTRIA CHIMICOFARMACEUTICA S.P.A. (IT) | 2000-09-26 | — | — | US | disclosed |
| EP-0865442-B1 | IMIDAZO[1,2-a]QUINOXALIN-4-AMINES ACTIVE AS ADENOSINE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOSCAMA BIOMED CHIM FARMA (IT) | 2000-07-05 | — | — | EP | disclosed |