Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30973438 | 0.80 | BRD4 (0.33) | CYP2C9CYP2C19NPSR1BRD4GRM5 | |
| SCHEMBL30973500 | 0.80 | GRM5 (0.34) | GRM5GRM1 | |
| SCHEMBL30973562 | 0.79 | HTR2A (0.36) | NPSR1FGFR1 | |
| SCHEMBL2994058 | 0.74 | MTNR1A (0.35) | BRD4MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL21060380 | 0.70 | KCNH2 (0.34) | CYP2C9CYP2C19NPSR1BRD4L3MBTL1 | |
| SCHEMBL30675219 | 0.70 | KCNH2 (0.34) | CYP2C9CYP2C19NPSR1BRD4L3MBTL1 | |
| SCHEMBL31370601 | 0.69 | MTNR1A (0.41) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL3109280 | 0.69 | MTNR1A (0.41) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL20689528 | 0.67 | L3MBTL1 (0.35) | CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL29361457 | 0.66 | GRIN2B (0.34) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |