Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30973540 | 0.80 | CYP2C9 (0.34) | GRM5GRM1 | |
| SCHEMBL30973562 | 0.77 | HTR2A (0.36) | HTR2A | |
| SCHEMBL30973521 | 0.74 | HTR2A (0.36) | HTR2AEHMT2EHMT1 | |
| SCHEMBL30973453 | 0.73 | CHRM1 (0.33) | — | |
| SCHEMBL30973594 | 0.72 | CHRM1 (0.35) | HTR2AEHMT2EHMT1 | |
| SCHEMBL30973438 | 0.71 | BRD4 (0.33) | GRM5GRM1 | |
| SCHEMBL30994357 | 0.70 | WDR5 (0.35) | GRM5GRM1 | |
| SCHEMBL31358051 | 0.64 | ESR2 (0.39) | GRM5GRM1 | |
| SCHEMBL30973284 | 0.63 | IL1B (0.37) | HTR2A | |
| SCHEMBL30833939 | 0.59 | IL1B (0.54) | EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |