Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | RAMP3 | O60896 | 12/20 | 0.42 |
| ▸ | CALCR | P30988 | 12/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31437158 | 0.88 | ACE (0.43) | ACERENOPRM1OPRK1EPHA2 | |
| SCHEMBL30471913 | 0.87 | OPRM1 (0.48) | ACEOPRM1OPRK1CXCR4 | |
| SCHEMBL31344445 | 0.86 | KEAP1 (0.51) | RAMP3CALCR | |
| SCHEMBL31410879 | 0.86 | NPY2R (0.47) | RAMP3CALCREPHA2 | |
| SCHEMBL30909415 | 0.86 | ACE (0.44) | ACERENOPRM1OPRK1CXCR4 | |
| SCHEMBL29994788 | 0.85 | OPRK1 (0.46) | ACEOPRM1OPRK1CXCR4 | |
| SCHEMBL29411971 | 0.85 | OPRK1 (0.46) | ACEOPRM1OPRK1CXCR4 | |
| SCHEMBL29575914 | 0.85 | RAMP3 (0.50) | RAMP3CALCR | |
| SCHEMBL30443975 | 0.85 | ACE (0.45) | ACERENRAMP3CALCREPHA2 | |
| SCHEMBL29839542 | 0.84 | RAMP3 (0.57) | RAMP3CALCROPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | claimed |